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Details on Person 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]

Class:Id	CatalystActivity:5655340
_displayName	1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]
_timestamp	2024-05-14 19:05:55
activeUnit	[EntityWithAccessionedSequence:74787] PIK3CA [cytosol] [Homo sapiens]
activity	[GO_MolecularFunction:78763] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity
created	[InstanceEdit:5655319] Rothfels, Karen, 2014-12-05
modified	[InstanceEdit:9633034] D'Eustachio, Peter, 2018-12-27 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9715688] Shorser, Solomon, 2021-02-17 [InstanceEdit:9715688] Shorser, Solomon, 2021-02-17 [InstanceEdit:9729976] Shorser, Solomon, 2021-05-05 [InstanceEdit:9729976] Shorser, Solomon, 2021-05-05 [InstanceEdit:9750461] Weiser, JD, 2021-08-11 [InstanceEdit:9750461] Weiser, JD, 2021-08-11 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15
physicalEntity	[Complex:5655267] Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] [Homo sapiens]
(catalystActivity)	[Reaction:5655235] Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3 [Homo sapiens]
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No pathways have been reviewed or authored by 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (5655340)