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Details on Person Activated FGFR1 mutants [plasma membrane]

Class:Id	DefinedSet:5655215
_displayName	Activated FGFR1 mutants [plasma membrane]
_timestamp	2016-01-22 13:42:52
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5655219] Rothfels, Karen, 2014-12-05
disease	[Disease:1500689] cancer [Disease:2032940] bone development disease
hasMember	[DefinedSet:1982041] Activated overexpressed FGFR1 homodimers [plasma membrane] [Homo sapiens] [Complex:1982038] Activated overexpressed FGFR1b homodimer [plasma membrane] [Homo sapiens] [Complex:1982036] Activated overexpressed FGFR1c homodimer [plasma membrane] [Homo sapiens] [CandidateSet:2023432] Activated FGFR1 mutant dimers with enhanced kinase activity [plasma membrane] [Homo sapiens] [Complex:2023426] p-8Y-FGFR1 K656E dimer [plasma membrane] [Homo sapiens] [Complex:2023428] p-8Y-FGFR1 N546K dimer [plasma membrane] [Homo sapiens] [Complex:2050642] Activated FGFR1c P252X mutants [plasma membrane] [Homo sapiens] [CandidateSet:8853273] Plasma membrane p-Y FGFR1 fusion dimers [plasma membrane] [Homo sapiens] [Complex:8853166] ERLIN2(1-185):p-8Y FGFR1(c.-88-822) fusion dimer [plasma membrane] [Homo sapiens] [Complex:8853243] p-6Y FGFR1(22-763):TACC1(571-805) fusion dimer [plasma membrane] [Homo sapiens]
modified	[InstanceEdit:8853279] Rothfels, Karen, 2016-01-22
name	Activated FGFR1 mutants
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5680817] R-HSA-5655215.2
(diseaseEntity)	[EntityFunctionalStatus:5655258] gain_of_function of Activated FGFR1 mutants [plasma membrane]
(hasComponent)	[Complex:5655216] Activated FGFR1 mutants:p-FRS2 [plasma membrane] [Homo sapiens] [Complex:5655296] Activated FGFR1 mutants:FRS2 [plasma membrane] [Homo sapiens]
(hasMember)	[DefinedSet:5691527] Activated FGFR1 mutants and fusions [plasma membrane] [Homo sapiens]
(input)	[Reaction:5655269] Activated FGFR1 mutants bind FRS2 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9893578] Update Tracker - [DefinedSet:5655215] Activated FGFR1 mutants [plasma membrane] - v56:[addHasMember, updateContainedMemberOrCandidate] [_UpdateTracker:9897101] Update Tracker - [DefinedSet:5655215] Activated FGFR1 mutants [plasma membrane] - v61:[updateContainedMemberOrCandidate] [_UpdateTracker:9898751] Update Tracker - [DefinedSet:5655215] Activated FGFR1 mutants [plasma membrane] - v64:[updateContainedMemberOrCandidate] [_UpdateTracker:9965140] Update Tracker - [DefinedSet:5655215] Activated FGFR1 mutants [plasma membrane] - v94:[updateContainedMemberOrCandidate]
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No pathways have been reviewed or authored by Activated FGFR1 mutants [plasma membrane] (5655215)