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Details on Person SPRTN binds monoUb:K164-PCNA associated with POLH

Class:Id	Reaction:5654986
_displayName	SPRTN binds monoUb:K164-PCNA associated with POLH
_doRelease	TRUE
_timestamp	2015-03-04 03:53:45
authored	[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5654983] Orlic-Milacic, Marija, 2014-12-04
edited	[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
input	[Complex:5654981] POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5643744] SPRTN [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5655038] Spartan/C1orf124, a reader of PCNA ubiquitylation and a regulator of UV-induced DNA damage response [LiteratureReference:5655012] Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesis [LiteratureReference:5655028] DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks
modified	[InstanceEdit:5655045] Orlic-Milacic, Marija, 2014-12-04 [InstanceEdit:5655121] Orlic-Milacic, Marija, 2014-12-04 [InstanceEdit:5656195] Orlic-Milacic, Marija, 2014-12-11 [InstanceEdit:5657556] Orlic-Milacic, Marija, 2014-12-13 [InstanceEdit:5663081] Orlic-Milacic, Marija, 2015-01-15 [InstanceEdit:5663087] Orlic-Milacic, Marija, 2015-01-15 [InstanceEdit:5663090] Orlic-Milacic, Marija, 2015-01-15 [InstanceEdit:5674553] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SPRTN binds monoUb:K164-PCNA associated with POLH
output	[Complex:5654984] SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:110319] Elongation by POLH [Homo sapiens] [Reaction:110317] Insertion of correct bases opposite the lesion by POLH [Homo sapiens]
releaseDate	2015-03-19
reviewed	[InstanceEdit:5663080] Borowiec, James, 2015-01-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5679877] R-HSA-5654986.2
summation	[Summation:5655014] SPRTN (Spartan, C1orf124, DVC1) contains a PIP box and a UBZ...
(hasEvent)	[Pathway:110320] Translesion Synthesis by POLH [Homo sapiens]
(precedingEvent)	[Reaction:5654985] SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH [Homo sapiens]
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