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Details on Person Activated FGFR1 binds SHC1

Class:IdReaction:5654573
_displayNameActivated FGFR1 binds SHC1
_doReleaseTRUE
_timestamp2015-03-04 04:13:45
authored[InstanceEdit:1489508] Rothfels, K, 2011-08-15
compartment[Compartment:70101] cytosol
[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:5654572] Rothfels, Karen, 2014-12-03
input[DefinedSet:5654170] Activated FGFR1 [plasma membrane] [Homo sapiens]
[DefinedSet:1169480] SHC1-2,SHC1-3 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:532244] Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells
[LiteratureReference:191036] Novel recruitment of Shc, Grb2, and Sos by fibroblast growth factor receptor-1 in v-Src-transformed cells
[LiteratureReference:191526] Signal transduction pathway of human fibroblast growth factor receptor 3. Identification of a novel 66-kDa phosphoprotein.
[LiteratureReference:532248] Indirect recruitment of the signalling adaptor Shc to the fibroblast growth factor receptor 2 (FGFR2)
modified[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActivated FGFR1 binds SHC1
output[Complex:5654258] Activated FGFR1:SHC1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2011-09-20
reviewed[InstanceEdit:1549563] Gotoh, N, 2011-08-26
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5680216] R-HSA-5654573.2
summation[Summation:1268224] Although a role for SHC1 in FGF signalling has been implicat...
(hasEvent)[Pathway:5654688] SHC-mediated cascade:FGFR1 [Homo sapiens]
(precedingEvent)[Reaction:5654582] Activated FGFR1 phosphorylates SHC1 [Homo sapiens]
(replacementInstances)[_Deleted:5655550] Deletion of instance: 1268226
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No pathways have been reviewed or authored by Activated FGFR1 binds SHC1 (5654573)