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Details on Person Activated FGFR4 binds PLCG1

Class:IdReaction:5654163
_displayNameActivated FGFR4 binds PLCG1
_doReleaseTRUE
_timestamp2015-03-04 03:55:56
authored[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18
compartment[Compartment:876] plasma membrane
created[InstanceEdit:5654153] Rothfels, Karen, 2014-12-03
edited[InstanceEdit:500337] Jupe, S, 2010-02-03
input[DefinedSet:5654158] Activated FGFR4 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:167682] PLCG1 [plasma membrane] [Homo sapiens]
[SimpleEntity:179838] PI(3,4,5)P3 [plasma membrane]
literatureReference[LiteratureReference:191028] Tyrosine 766 in the fibroblast growth factor receptor-1 is required for FGF-stimulation of phospholipase C, phospholipase D, phospholipase A(2), phosphoinositide 3-kinase and cytoskeletal reorganisation in porcine aortic endothelial cells
[LiteratureReference:190978] Intracellular retention, degradation, and signaling of glycosylation-deficient FGFR2 and craniosynostosis syndrome-associated FGFR2C278F
modified[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActivated FGFR4 binds PLCG1
output[Complex:5654166] activated FGFR4:PLCG1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2010-03-16
reviewed[InstanceEdit:192607] Mohammadi, M, 2007-02-06 21:44:35
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5679907] R-HSA-5654163.2
summation[Summation:191500] Recruitment of PLC-gamma by FGF receptors has been best stud...
(hasEvent)[Pathway:5654228] Phospholipase C-mediated cascade; FGFR4 [Homo sapiens]
(normalReaction)[Reaction:5655313] Activated FGFR4 mutants bind PLCG1 [Homo sapiens]
(precedingEvent)[Reaction:5654151] Activated FGFR4 phosphorylates PLCG1 [Homo sapiens]
(replacementInstances)[_Deleted:5655557] Deletion of instance: 190896
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No pathways have been reviewed or authored by Activated FGFR4 binds PLCG1 (5654163)