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Details on Person Ragulator:Rag dimers:SLC38A9 bind mTORC1

Class:Id	Reaction:5653968
_displayName	Ragulator:Rag dimers:SLC38A9 bind mTORC1
_doRelease	TRUE
_timestamp	2016-12-16 13:14:56
authored	[InstanceEdit:5671717] Jupe, Steve, 2015-02-02
compartment	[Compartment:17938] lysosomal membrane [Compartment:70101] cytosol
created	[InstanceEdit:5653975] Jupe, Steve, 2014-12-03
edited	[InstanceEdit:5693051] Jupe, Steve, 2015-05-13
input	[Complex:8952725] Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] [Homo sapiens] [Complex:377400] mTORC1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5653913] Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
modified	[InstanceEdit:5655428] Jupe, Steve, 2014-12-05 [InstanceEdit:5656349] Jupe, Steve, 2014-12-12 [InstanceEdit:5687546] Jupe, Steve, 2015-04-08 [InstanceEdit:5687631] Jupe, Steve, 2015-04-08 [InstanceEdit:5693184] Jupe, Steve, 2015-05-14 [InstanceEdit:8952705] Jassal, Bijay, 2016-12-16 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Ragulator:Rag dimers:SLC38A9 bind mTORC1
output	[Complex:5653972] mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] [Homo sapiens]
precedingEvent	[Reaction:8952716] SLC38A9 binds Ragulator:Rag dimers [Homo sapiens] [Reaction:5653974] Ragulator binds Rag dimers [Homo sapiens]
releaseDate	2015-06-17
releaseStatus	NEW
reviewed	[InstanceEdit:5693188] Zwartkruis, Fried J T, 2015-05-14
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5687545] Jupe, Steve, 2015-04-08
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5695687] R-HSA-5653968.3
summation	[Summation:5655433] The Ragulator complex on the lysosomal surface binds Rag het...
(hasEvent)	[Pathway:165159] MTOR signalling [Homo sapiens]
(precedingEvent)	[Reaction:165680] Formation of active mTORC1 complex [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781841] Update Tracker - [Reaction:5653968] Ragulator:Rag dimers:SLC38A9 bind mTORC1 - v60:[add_removeInput]
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No pathways have been reviewed or authored by Ragulator:Rag dimers:SLC38A9 bind mTORC1 (5653968)