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Details on Person Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I

Class:IdLiteratureReference:5653877
_displayNameCrystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I
_timestamp2014-12-02 18:47:27
author[Person:5653895] Ramakrishnan, B
[Person:5653892] Qasba, Pradman K
created[InstanceEdit:5653879] D'Eustachio, Peter, 2014-12-02
journalJ. Mol. Biol.
pages205-18
pubMedIdentifier11419947
titleCrystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I
volume310
year2001
(literatureReference)[Reaction:5653878] B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac [Homo sapiens]
[Reaction:5653886] B4GALT1 binds LALBA [Homo sapiens]
[Complex:5653885] B4GALT1:LALBA [Golgi membrane] [Homo sapiens]
[RegulationReference:9641506] Positive regulation by 'Mn2+ [Golgi lumen]' Lactose biosynthesis
[RegulationReference:9642727] Positive regulation by 'UDP-Gal [Golgi lumen]' Lactose biosynthesis
[CatalystActivityReference:9643898] lactose synthase activity of B4GALT1:LALBA [Golgi membrane] Lactose biosynthesis
[CatalystActivityReference:9941991] enzyme-substrate adaptor activity of LALBA [Golgi lumen] Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I
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