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Details on Person POLD,POLE complete replication of damaged DNA after TLS

Class:IdReaction:5653840
_displayNamePOLD,POLE complete replication of damaged DNA after TLS
_doReleaseTRUE
_timestamp2015-03-04 03:44:10
authored[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
catalystActivity[CatalystActivity:5653836] DNA-directed DNA polymerase activity of PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5653839] Orlic-Milacic, Marija, 2014-12-02
edited[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
input[Complex:5653837] PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] [Homo sapiens]
[SimpleEntity:30555] dNTP [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:5653648] Modification of PCNA by ISG15 plays a crucial role in termination of error-prone translesion DNA synthesis
modified[InstanceEdit:5663081] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663087] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663090] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5674553] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePOLD,POLE complete replication of damaged DNA after TLS
output[DefinedSet:5652135] Damaged dsDNA [nucleoplasm] [Homo sapiens]
[Complex:5651799] PCNA:POLD,POLE:RPA:RFC [nucleoplasm] [Homo sapiens]
[SimpleEntity:113541] PPi [nucleoplasm]
precedingEvent
releaseDate2015-03-19
reviewed[InstanceEdit:5663080] Borowiec, James, 2015-01-07
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5679697] R-HSA-5653840.2
summation[Summation:5653815] After DNA damage is bypassed by error-prone DNA polymerases ...
(hasEvent)[Pathway:5656169] Termination of translesion DNA synthesis [Homo sapiens]
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No pathways have been reviewed or authored by POLD,POLE complete replication of damaged DNA after TLS (5653840)