Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA

Class:IdReaction:5653754
_displayNameUBE2L6:TRIM25 ISGylates monoUb:K164-PCNA
_doReleaseTRUE
_timestamp2015-03-04 04:13:56
authored[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
catalystActivity[CatalystActivity:5653763] ISG15 transferase activity of UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5653758] Orlic-Milacic, Marija, 2014-12-01
edited[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
input[Complex:5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] [Homo sapiens]
[Complex:5653757] ISG15:UBA7 [nucleoplasm] [Homo sapiens]
[Complex:5653757] ISG15:UBA7 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5653648] Modification of PCNA by ISG15 plays a crucial role in termination of error-prone translesion DNA synthesis
modified[InstanceEdit:5657556] Orlic-Milacic, Marija, 2014-12-13
[InstanceEdit:5663021] Orlic-Milacic, Marija, 2015-01-14
[InstanceEdit:5663081] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663087] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5663090] Orlic-Milacic, Marija, 2015-01-15
[InstanceEdit:5674553] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameUBE2L6:TRIM25 ISGylates monoUb:K164-PCNA
output[Complex:5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] [Homo sapiens]
[Complex:5653664] UBE2L6:TRIM25 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:5653762] UBA7 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:5653762] UBA7 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2015-03-19
reviewed[InstanceEdit:5663080] Borowiec, James, 2015-01-07
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5680221] R-HSA-5653754.2
summation[Summation:5653755] The complex of ISG15 E2 conjugating enzyme UBE2L6 (UBCH8) an...
(hasEvent)[Pathway:5656169] Termination of translesion DNA synthesis [Homo sapiens]
(precedingEvent)[Reaction:5653766] USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (5653754)