Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Fructose is found in fruits, is one of the components of the...

Class:IdSummation:5653569
_displayNameFructose is found in fruits, is one of the components of the...
_timestamp2015-08-27 22:35:30
created[InstanceEdit:5653562] D'Eustachio, Peter, 2014-11-29
modified[InstanceEdit:5653571] D'Eustachio, Peter, 2014-11-29
[InstanceEdit:5666057] D'Eustachio, Peter, 2015-01-20
[InstanceEdit:6792826] D'Eustachio, Peter, 2015-08-27
textFructose is found in fruits, is one of the components of the disaccharide sucrose, and is a widely used sweetener in processed foods. Dietary fructose is catabolized in the liver via fructose 1-phosphate to yield dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, which then are converted to pyruvate via steps of canonical glycolysis (Hers & Kusaka 1953; Sillero et al. 1969). Excessive dietary intake of fructose and its metabolism have been associated with major disease risks in humans, although this issue remains controversial (Kolderup & Svihus 2015; DiNicolantonio et al. 2015; Bray 2013; Mayes 1993; Rippe & Angelopoulos 2013; van Buul et al. 2013). Fructose can also be synthesized from glucose via the polyol pathway (Hers 1960; Oates 2008). This synthetic process provides the fructose found in seminal fluid and, in other tissues, can contribute to pathologies of diabetes.
(summation)[Pathway:5652084] Fructose metabolism [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Fructose is found in fruits, is one of the components of the... (5653569)