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Details on Person Cytosolic SORD (sorbitol dehydrogenase) catalyzes the reacti...
| Class:Id | Summation:5652198 |
|---|---|
| _displayName | Cytosolic SORD (sorbitol dehydrogenase) catalyzes the reacti... |
| _timestamp | 2015-01-29 14:41:23 |
| created | [InstanceEdit:5652219] D'Eustachio, Peter, 2014-11-28 |
| modified | [InstanceEdit:5652228] D'Eustachio, Peter, 2014-11-28 [InstanceEdit:5668911] Jassal, Bijay, 2015-01-29 |
| text | Cytosolic SORD (sorbitol dehydrogenase) catalyzes the reaction of D-sorbitol and NAD+ to form fructose (Fru) and NADH + H+. This reaction was first described by Hers (1960) in sheep seminal vesicles; the human enzyme was identified by O'Brien et al. (1983). The active enzyme is a tetramer with four associated Zn2+ ions (Pauly et al. 2003) whose amino-terminal methionine residue has been removed (Karlsson et al. 1989). |
| (summation) | [Reaction:5652195] SORD oxidizes D-sorbitol to Fru [Homo sapiens] |
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No pathways have been reviewed or authored by Cytosolic SORD (sorbitol dehydrogenase) catalyzes the reacti... (5652198)
