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Details on Person LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA

Class:Id	Reaction:5651809
_displayName	LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA
_doRelease	TRUE
_timestamp	2017-04-28 16:15:34
authored	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5651806] Orlic-Milacic, Marija, 2014-11-24
edited	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input	[Complex:5651810] LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:111248] Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). [LiteratureReference:111254] AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair. [LiteratureReference:5358859] Mechanism underlying replication protein a stimulation of DNA ligase I
modified	[InstanceEdit:5651813] Orlic-Milacic, Marija, 2014-11-24 [InstanceEdit:5651909] Orlic-Milacic, Marija, 2014-11-25 [InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:8986546] Orlic-Milacic, Marija, 2017-04-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA
output	[GenomeEncodedEntity:5649637] dsDNA [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:53787] LIG1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:50119] APEX1 [nucleoplasm] [Homo sapiens] [Complex:5651799] PCNA:POLD,POLE:RPA:RFC [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:5651805] LIG1 bound to APEX1 and PCNA ligates SSB [Homo sapiens] [Reaction:110371] LIG1 binds APEX1 and PCNA at SSB [Homo sapiens]
releaseDate	2004-03-06
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5680339] R-HSA-5651809.3
summation	[Summation:5651908] After the PCNA-dependent long patch base excision (BER) is c...
(hasEvent)	[Pathway:5651801] PCNA-Dependent Long Patch Base Excision Repair [Homo sapiens]
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No pathways have been reviewed or authored by LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA (5651809)