Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person LIG1 bound to APEX1 and PCNA ligates SSB

Class:Id	Reaction:5651805
_displayName	LIG1 bound to APEX1 and PCNA ligates SSB
_doRelease	TRUE
_timestamp	2015-03-04 04:21:52
authored	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
catalystActivity	[CatalystActivity:5651803] DNA ligase activity of LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5651806] Orlic-Milacic, Marija, 2014-11-24
edited	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input	[Complex:5651808] LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:111248] Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). [LiteratureReference:111254] AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair. [LiteratureReference:5358863] DNA ligases: structure, reaction mechanism, and function [LiteratureReference:5358859] Mechanism underlying replication protein a stimulation of DNA ligase I
modified	[InstanceEdit:5651813] Orlic-Milacic, Marija, 2014-11-24 [InstanceEdit:5651906] Orlic-Milacic, Marija, 2014-11-25 [InstanceEdit:5651909] Orlic-Milacic, Marija, 2014-11-25 [InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	LIG1 bound to APEX1 and PCNA ligates SSB
output	[Complex:5651810] LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:110371] LIG1 binds APEX1 and PCNA at SSB [Homo sapiens] [Reaction:110363] FEN1 bound to PCNA and APEX1 cleaves flap ssDNA [Homo sapiens]
releaseDate	2004-03-06
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5680359] R-HSA-5651805.2
summation	[Summation:5651886] LIG1 (DNA ligase 1) is recruited to the long-patch base exci...
(hasEvent)	[Pathway:5651801] PCNA-Dependent Long Patch Base Excision Repair [Homo sapiens]
(precedingEvent)	[Reaction:5651809] LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA [Homo sapiens]
(replacementInstances)	[_Deleted:5676181] Deletion of instance: 110370
[Change default viewing format]

No pathways have been reviewed or authored by LIG1 bound to APEX1 and PCNA ligates SSB (5651805)