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Details on Person POLB-bound FEN1 (flap endonuclease) cleaves the displaced DN...

Class:IdSummation:5651779
_displayNamePOLB-bound FEN1 (flap endonuclease) cleaves the displaced DN...
_timestamp2014-11-26 05:14:33
created[InstanceEdit:5651765] Orlic-Milacic, Marija, 2014-11-24
modified[InstanceEdit:5651872] Orlic-Milacic, Marija, 2014-11-25
[InstanceEdit:5651876] Orlic-Milacic, Marija, 2014-11-25
[InstanceEdit:5651937] Orlic-Milacic, Marija, 2014-11-26
textPOLB-bound FEN1 (flap endonuclease) cleaves the displaced DNA strand (flap structure), which contains the damaged AP residue that could not be excised by POLB (DNA polymerase beta) (Klungland and Lindahl 1997, Prasad et al. 2001, Liu et al. 2005).
(summation)[Reaction:5651782] FEN1 bound to POLB cleaves displaced DNA strand (flap) [Homo sapiens]
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