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Details on Person Defective SLC34A2 does not cotransport Pi, 3Na+
| Class:Id | FailedReaction:5651697 |
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| _displayName | Defective SLC34A2 does not cotransport Pi, 3Na+ |
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| _doRelease | TRUE |
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| _timestamp | 2015-09-04 20:50:43 |
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| authored | [InstanceEdit:5651695] Jassal, Bijay, 2014-11-24 |
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| catalystActivity | [CatalystActivity:9631803] sodium:phosphate symporter activity of SLC34A2 mutants [plasma membrane] |
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| compartment | [Compartment:984] extracellular region
[Compartment:876] plasma membrane |
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| created | [InstanceEdit:5651695] Jassal, Bijay, 2014-11-24 |
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| disease | [Disease:5651682] pulmonary alveolar microlithiasis |
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| edited | [InstanceEdit:5651695] Jassal, Bijay, 2014-11-24 |
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| entityFunctionalStatus | [EntityFunctionalStatus:5651706] loss_of_function of SLC34A2 mutants [plasma membrane] |
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| input | [SimpleEntity:109277] Pi [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region] |
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| isChimeric | FALSE |
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| literatureReference | [LiteratureReference:5651704] [A novel mutation of the SLC34A2 gene in a Chinese pedigree with pulmonary alveolar microlithiasis]
[LiteratureReference:427624] Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis |
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| modified | [InstanceEdit:5663019] Jassal, Bijay, 2015-01-14
[InstanceEdit:6789777] Jassal, Bijay, 2015-08-04
[InstanceEdit:9631717] Wu, G, 2018-12-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 |
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| name | Defective SLC34A2 does not cotransport Pi, 3Na+ |
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| normalReaction |
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| releaseDate | 2015-09-22 |
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| releaseStatus | NEW |
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| reviewed | [InstanceEdit:6789776] Broer, Stefan, 2015-08-04 |
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| reviewStatus | [ReviewStatus:9821382] five stars |
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| species | [Species:48887] Homo sapiens |
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| stableIdentifier | [StableIdentifier:6797156] R-HSA-5651697.3 |
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| summation | [Summation:5651696] SLC34A1 and 2 encode Na+/Pi cotransporters, which cotranspor... |
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| (hasEvent) | [Pathway:5619045] Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) [Homo sapiens] |
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| (updatedInstance) | [_UpdateTracker:9778538] Update Tracker - [FailedReaction:5651697] Defective SLC34A2 does not cotransport Pi, 3Na+ - v68:[addCatalystActivity] |
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