Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm]

Class:IdComplex:5649733
_displayNameNEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm]
_timestamp2015-03-04 06:07:08
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5649732] Orlic-Milacic, Marija, 2014-11-21
hasComponent
isChimericFALSE
literatureReference[LiteratureReference:5649703] AP endonuclease-independent DNA base excision repair in human cells
[LiteratureReference:5649714] NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells
nameNEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5681719] R-HSA-5649733.1
(input)[Reaction:5649734] LIG3 ligates NEIL1,NEIL2-generated single strand break [Homo sapiens]
(output)[Reaction:5649723] POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution [Homo sapiens]
(physicalEntity)[CatalystActivity:5649721] DNA ligase activity of NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm]
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No pathways have been reviewed or authored by NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA [nucleoplasm] (5649733)