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Details on Person AP endonuclease-independent DNA base excision repair in human cells

Class:IdLiteratureReference:5649703
_displayNameAP endonuclease-independent DNA base excision repair in human cells
_timestamp2014-11-20 20:38:49
author[Person:5649695] Wiederhold, Lee
[Person:5649699] Leppard, John B
[Person:110774] Kedar, P
[Person:76732] Karimi-Busheri, F
[Person:76739] Rasouli-Nia, A
[Person:76733] Weinfeld, M
[Person:5358561] Tomkinson, Alan E
[Person:5649662] Izumi, Tadahide
[Person:5649698] Prasad, Rajendra
[Person:5649696] Wilson, Samuel H
[Person:5649676] Mitra, Sankar
[Person:5649665] Hazra, Tapas K
created[InstanceEdit:5649694] Orlic-Milacic, Marija, 2014-11-20
journalMol. Cell
pages209-20
pubMedIdentifier15260972
titleAP endonuclease-independent DNA base excision repair in human cells
volume15
year2004
(literatureReference)[Pathway:73933] Resolution of Abasic Sites (AP sites) [Homo sapiens]
[Reaction:5649701] NEIL1,NEIL2 displace OGG1 from AP-dsDNA [Homo sapiens]
[Pathway:5649702] APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway [Homo sapiens]
[Reaction:5649705] PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) [Homo sapiens]
[Reaction:5649708] NEIL1,NEIL2 recruits POLB to incised AP site [Homo sapiens]
[Reaction:5649711] NEIL1,NEIL2 incises DNA strand 5' to the AP site [Homo sapiens]
[Reaction:5649723] POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution [Homo sapiens]
[Reaction:5649724] LIG3:XRCC1, POLB, NEIL1,NEIL2 and PNKP dissociate from the BER site [Homo sapiens]
[Reaction:5649725] POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) [Homo sapiens]
[Reaction:5649726] LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA [Homo sapiens]
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