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Details on Person NEIL1,NEIL2 displace OGG1 from AP-dsDNA

Class:IdReaction:5649701
_displayNameNEIL1,NEIL2 displace OGG1 from AP-dsDNA
_doReleaseTRUE
_timestamp2017-04-28 15:44:22
authored[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5649694] Orlic-Milacic, Marija, 2014-11-20
edited[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
input[CandidateSet:5649697] NEIL1,NEIL2 [nucleoplasm] [Homo sapiens]
[Complex:110195] OGG1:AP-dsDNA [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5649703] AP endonuclease-independent DNA base excision repair in human cells
[LiteratureReference:5649660] Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA
[LiteratureReference:5649684] Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions
modified[InstanceEdit:5674223] Orlic-Milacic, Marija, 2015-02-11
[InstanceEdit:5674541] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:8986533] Orlic-Milacic, Marija, 2017-04-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNEIL1,NEIL2 displace OGG1 from AP-dsDNA
output[Complex:5649693] NEIL1,NEIL2:AP-dsDNA [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:60887] OGG1 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2015-03-19
reviewed[InstanceEdit:5673689] Borowiec, James, 2014-12-22
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5679986] R-HSA-5649701.3
summation[Summation:5649700] Although NEIL1 and NEIL2 have a weak 8-oxoguanine glycosylas...
(hasEvent)[Pathway:5649702] APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway [Homo sapiens]
(precedingEvent)[Reaction:5649711] NEIL1,NEIL2 incises DNA strand 5' to the AP site [Homo sapiens]
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No pathways have been reviewed or authored by NEIL1,NEIL2 displace OGG1 from AP-dsDNA (5649701)