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Details on Person Don't release - WHSC1 methylates methyl-lysine-45 of histone H4 (H4K44)

Class:Id	Reaction:5643682
_displayName	Don't release - WHSC1 methylates methyl-lysine-45 of histone H4 (H4K44)
_doRelease	FALSE
_timestamp	2017-02-27 11:07:27
authored	[InstanceEdit:3214866] Jupe, S, 2013-03-12
catalystActivity	[CatalystActivity:5159247] histone H3 methyltransferase activity of WHSC1, WHSC1L1 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5643684] Jupe, Steve, 2014-11-17
edited	[InstanceEdit:5622078] Jupe, Steve, 2014-09-10
input	[EntityWithAccessionedSequence:5159239] MeK45-HIST1H4 [nucleoplasm] [Homo sapiens] [SimpleEntity:77087] AdoMet [nucleoplasm]
isChimeric	FALSE
literatureReference	[LiteratureReference:3301907] The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate
modified	[InstanceEdit:5643685] Jupe, Steve, 2014-11-17 [InstanceEdit:5651717] Jupe, Steve, 2014-11-24 [InstanceEdit:5651816] Jupe, Steve, 2014-11-25 [InstanceEdit:5669201] Jupe, Steve, 2015-01-30 [InstanceEdit:5674398] Jupe, Steve, 2015-02-12 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8979544] Jupe, Steve, 2017-02-27
name	Don't release - WHSC1 methylates methyl-lysine-45 of histone H4 (H4K44)
output	[EntityWithAccessionedSequence:5251401] Me2K45-HIST1H4 [nucleoplasm] [Homo sapiens] [SimpleEntity:77502] AdoHcy [nucleoplasm]
reviewed	[InstanceEdit:5643671] Motamedi, Mo, 2014-11-17
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8886472] R-HSA-5643682.1
summation	[Summation:5643683] WHSC1 (NSD2/MMSET) is one of several lysine methyltransferas...
systematicName	WHSC1 transfers CH3 from AdoMet to MeK45-HIST1H4
(hasEvent)	[Pathway:3214841] PKMTs methylate histone lysines [Homo sapiens]
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No pathways have been reviewed or authored by Don't release - WHSC1 methylates methyl-lysine-45 of histone H4 (H4K44) (5643682)