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Details on Person RP2 binds ARL3:GTP:UNC119B

Class:IdReaction:5638004
_displayNameRP2 binds ARL3:GTP:UNC119B
_doReleaseTRUE
_timestamp2016-11-06 23:52:56
authored[InstanceEdit:5638001] Rothfels, Karen, 2014-10-30
compartment[Compartment:18730] cilium
created[InstanceEdit:5638008] Rothfels, Karen, 2014-11-13
edited[InstanceEdit:5626894] Jassal, Bijay, 2014-10-13
input[Complex:5624076] ARL3:GTP:UNC119B [cilium] [Homo sapiens]
[EntityWithAccessionedSequence:5624052] RP2 [cilium] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5624006] Specificity of Arl2/Arl3 signaling is mediated by a ternary Arl3-effector-GAP complex
[LiteratureReference:5624002] Localization of retinitis pigmentosa 2 to cilia is regulated by Importin beta2
[LiteratureReference:5624015] The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium
[LiteratureReference:5623984] An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium
[LiteratureReference:5624013] The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3
[LiteratureReference:5623996] Crystal structure of the human retinitis pigmentosa 2 protein and its interaction with Arl3
[LiteratureReference:5623331] The emerging role of Arf/Arl small GTPases in cilia and ciliopathies
[LiteratureReference:5623989] Arl3 and RP2 mediated assembly and traffic of membrane associated cilia proteins
modified[InstanceEdit:5638422] Rothfels, Karen, 2014-11-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRP2 binds ARL3:GTP:UNC119B
output[Complex:5637985] RP2:ARL3:GTP:UNC119B [cilium] [Homo sapiens]
precedingEvent
releaseDate2014-12-11
reviewed[InstanceEdit:5637996] Lorentzen, Esben, 2014-11-10
[InstanceEdit:5638370] Goncalves, Joao, 2014-11-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5622671] R-HSA-5638004.2
summation[Summation:5624039] RP2 is an ARL3 GAP that is localized to the cilium and plays...
(hasEvent)[Pathway:5624138] Trafficking of myristoylated proteins to the cilium [Homo sapiens]
(precedingEvent)[Reaction:5638007] RP2 activates the GTPase activity of ARL3 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9782196] Update Tracker - [Reaction:5638004] RP2 binds ARL3:GTP:UNC119B - v59:[modifyText]
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No pathways have been reviewed or authored by RP2 binds ARL3:GTP:UNC119B (5638004)