Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person GLI proteins bind PTCH1 gene

Class:Id	Reaction:5635848
_displayName	GLI proteins bind PTCH1 gene
_doRelease	TRUE
_timestamp	2016-11-10 16:36:37
authored	[InstanceEdit:5633210] Rothfels, Karen, 2014-10-30
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5635849] Rothfels, Karen, 2014-11-07
edited	[InstanceEdit:5633134] Gillespie, Marc E, 2014-10-30
input	[DefinedSet:5635077] 2p-GLI1,2,3 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5612503] PTCH1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5612467] A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb [LiteratureReference:5612477] Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning [LiteratureReference:5612485] Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis [LiteratureReference:5612471] Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site [LiteratureReference:5358220] Gli proteins in development and disease
modified	[InstanceEdit:5636029] Rothfels, Karen, 2014-11-09 [InstanceEdit:8948120] Rothfels, Karen, 2016-11-10 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	GLI proteins bind PTCH1 gene
output	[Complex:5635085] 2p-GLI:PTCH1 gene [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:5635841] GLI proteins are phosphorylated [Homo sapiens] [BlackBoxEvent:5635843] GLI translocates to the nucleus [Homo sapiens]
releaseDate	2014-12-11
reviewed	[InstanceEdit:5636011] Liu, Yulu Cherry, 2014-11-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6781720] R-HSA-5635848.3
summation	[Summation:5635787] PTCH1 has been identified as a Hh-responsive target in a num...
(hasEvent)	[Pathway:5635851] GLI proteins bind promoters of Hh responsive genes to promote transcription [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by GLI proteins bind PTCH1 gene (5635848)