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Details on Person Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase

Class:IdLiteratureReference:5634936
_displayNameMultiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase
_timestamp2014-11-06 20:58:22
author[Person:5624796] Zhang, Qing
[Person:5634935] Shi, Qing
[Person:5610165] Chen, Yongbin
[Person:5610282] Yue, Tao
[Person:5610171] Li, Shuang
[Person:5610167] Wang, Bing
[Person:5358081] Jiang, Jin
created[InstanceEdit:5634934] Rothfels, Karen, 2014-11-06
journalProc. Natl. Acad. Sci. U.S.A.
pages21191-6
pubMedIdentifier19955409
titleMultiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase
volume106
year2009
(literatureReference)[BlackBoxEvent:5635841] GLI proteins are phosphorylated [Homo sapiens]
[BlackBoxEvent:5635854] GLI2,3 are degraded by the proteasome [Homo sapiens]
[Reaction:5635855] phosphorylated GLI proteins bind SPOP:CUL3:RBX1 [Homo sapiens]
[Reaction:5635856] SPOP:CUL3:RBX1 ubiquitinates GLI2,3 [Homo sapiens]
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