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Details on Person EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9)

Class:IdReaction:5634729
_displayNameEHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9)
_doReleaseTRUE
_timestamp2015-03-04 03:53:18
authored[InstanceEdit:3214866] Jupe, S, 2013-03-12
catalystActivity[CatalystActivity:5634755] histone H3 methyltransferase activity of EHMT1:EHMT2 [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5634718] Jupe, Steve, 2014-11-05
edited[InstanceEdit:5622078] Jupe, Steve, 2014-09-10
input[CandidateSet:4827376] MeK10-histone H3 [nucleoplasm] [Homo sapiens]
[SimpleEntity:77087] AdoMet [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:3301891] G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis
[LiteratureReference:427757] Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains
modified[InstanceEdit:5634764] Jupe, Steve, 2014-11-06
[InstanceEdit:5634799] Jupe, Steve, 2014-11-06
[InstanceEdit:5637656] Jupe, Steve, 2014-11-12
[InstanceEdit:5638320] Jupe, Steve, 2014-11-13
[InstanceEdit:5638348] Jupe, Steve, 2014-11-14
[InstanceEdit:5643672] Jupe, Steve, 2014-11-17
[InstanceEdit:5643684] Jupe, Steve, 2014-11-17
[InstanceEdit:5651717] Jupe, Steve, 2014-11-24
[InstanceEdit:5651816] Jupe, Steve, 2014-11-25
[InstanceEdit:5669142] Jupe, Steve, 2015-01-30
[InstanceEdit:5674563] Jupe, Steve, 2015-02-13
[InstanceEdit:5676065] Jupe, Steve, 2015-02-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameEHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9)
EHMT1:EHMT2 (KMT1D:KMT1C) methylates MeK10-histone H3 (H3K9)
EHMT1:EHMT2 methylates MeK10-histone H3
output[CandidateSet:5634724] Me2K10-histone H3 [nucleoplasm] [Homo sapiens]
[SimpleEntity:77502] AdoHcy [nucleoplasm]
releaseDate2015-03-15
reviewed[InstanceEdit:5643671] Motamedi, Mo, 2014-11-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5644762] R-HSA-5634729.2
summation[Summation:5634759] EHMT2 (KMT1C, G9A) and EHMT1 (KMT1D, GLP) are the euchromati...
systematicNameEHMT1:EHMT2:WIZ transfers CH3 from AdoMet to MeK10-replicative histone H3
(hasEvent)[Pathway:3214841] PKMTs methylate histone lysines [Homo sapiens]
(updatedInstance)[_UpdateTracker:9785476] Update Tracker - [Reaction:5634729] EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) - v52:[modifyText]
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