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Details on Person UniProt:Q6YV23 CARA
| Class:Id | ReferenceGeneProduct:5633267 |
|---|---|
| _chainChangeLog | transit peptide:1-50 added on Fri February 6 2015;chain:51-446 added on Fri February 6 2015 |
| _displayName | UniProt:Q6YV23 CARA |
| _timestamp | 2025-02-21 18:44:52 |
| chain | transit peptide:1-50 chain:51-446 |
| checksum | E529103D9D4D3A47 |
| comment | FUNCTION Small subunit of the arginine-specific carbamoyl phosphate synthase (CPSase). CPSase catalyzes the formation of carbamoyl phosphate from the ammonia moiety of glutamine, carbonate, and phosphate donated by ATP, the first step of the arginine biosynthetic pathway. The small subunit (glutamine amidotransferase) binds and cleaves glutamine to supply the large subunit with the substrate ammonia.CATALYTIC ACTIVITY hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)CATALYTIC ACTIVITY L-glutamine + H2O = L-glutamate + NH4(+)PATHWAY Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.PATHWAY Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.SUBUNIT Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.SUBCELLULAR LOCATION Belongs to the CarA family.SEQUENCE CAUTION Intron retention. |
| created | [InstanceEdit:5633271] Amarasinghe, Vindhya, 2014-10-31 |
| description | recommendedName: Carbamoyl phosphate synthase small chain, chloroplastic ecNumber: 6.3.5.5 alternativeName: Carbamoyl phosphate synthetase glutamine chain |
| geneName | CARA Os02g0708100 LOC_Os02g47850 OSJNBb0060O16.25 |
| identifier | Q6YV23 |
| isSequenceChanged | FALSE |
| keyword | Amino-acid biosynthesis Arginine biosynthesis ATP-binding Chloroplast Glutamine amidotransferase Ligase Nucleotide-binding Plastid Pyrimidine biosynthesis Reference proteome Transit peptide |
| modified | [InstanceEdit:5633285] Amarasinghe, Vindhya, 2014-10-31 [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | CARA |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | CARA_ORYSJ Q6YV24 Q8S3R8 |
| sequenceLength | 446 |
| species | [Species:186860] Oryza sativa |
| (referenceEntity) | [EntityWithAccessionedSequence:5633270] LOC_Os02g47850 [cytosol] [Oryza sativa] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q6YV23 CARA (5633267)
