Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person SLC2A1 tetramer does not transport Glc from extracellular region to cytosol

Class:IdFailedReaction:5632804
_displayNameSLC2A1 tetramer does not transport Glc from extracellular region to cytosol
_doReleaseTRUE
_timestamp2017-05-12 16:57:02
authored[InstanceEdit:5632829] Jassal, Bijay, 2014-10-29
catalystActivity[CatalystActivity:9631917] D-glucose transmembrane transporter activity of SLC2A1 mutants [plasma membrane]
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:5632829] Jassal, Bijay, 2014-10-29
disease[Disease:5632824] early infantile epileptic encephalopathy
edited[InstanceEdit:5632829] Jassal, Bijay, 2014-10-29
entityFunctionalStatus[EntityFunctionalStatus:5632863] loss_of_function of SLC2A1 mutants [plasma membrane]
input[SimpleEntity:70115] Glc [extracellular region]
isChimericFALSE
literatureReference[LiteratureReference:5632774] Glut1 deficiency: inheritance pattern determined by haploinsufficiency
[LiteratureReference:5632808] GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrier
[LiteratureReference:5632832] Early-onset absence epilepsy caused by mutations in the glucose transporter GLUT1
modified[InstanceEdit:5663019] Jassal, Bijay, 2015-01-14
[InstanceEdit:6789777] Jassal, Bijay, 2015-08-04
[InstanceEdit:8981584] D'Eustachio, Peter, 2017-03-10
[InstanceEdit:9006096] D'Eustachio, Peter, 2017-05-12
[InstanceEdit:9631717] Wu, G, 2018-12-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSLC2A1 tetramer does not transport Glc from extracellular region to cytosol
normalReaction
releaseDate2015-09-22
releaseStatusNEW
reviewed[InstanceEdit:6789776] Broer, Stefan, 2015-08-04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6797150] R-HSA-5632804.4
summation[Summation:5632846] Members of the SLC2A family encode glucose transporter (GLUT...
(hasEvent)[Pathway:5619043] Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) [Homo sapiens]
(updatedInstance)[_UpdateTracker:9778026] Update Tracker - [FailedReaction:5632804] SLC2A1 tetramer does not transport Glc from extracellular region to cytosol - v68:[addCatalystActivity]
[Change default viewing format]
No pathways have been reviewed or authored by SLC2A1 tetramer does not transport Glc from extracellular region to cytosol (5632804)
Follow Reactome