Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person SMURF 1 and 2 are required in a redundant manner for the lig...
| Class:Id | Summation:5632439 |
|---|---|
| _displayName | SMURF 1 and 2 are required in a redundant manner for the lig... |
| _timestamp | 2014-10-28 14:53:14 |
| created | [InstanceEdit:5632438] Rothfels, Karen, 2014-10-28 |
| text | SMURF 1 and 2 are required in a redundant manner for the ligand-dependent ubiquitination of the C-terminal tail of PTCH. Ubiquitination is required for PTCH1 clearance from the primary cilium to endocytic compartments for degradation, allowing downstream pathway activation (Rohatgi et al, 2007; Yue et al, 2014; Huang et al, 2013). |
| (summation) | [Reaction:5632648] SMURF1/2 ubiquitinates PTCH1 [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by SMURF 1 and 2 are required in a redundant manner for the lig... (5632439)
