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Details on Person SESN1,2,3 bind AMPK

Class:IdReaction:5631941
_displayNameSESN1,2,3 bind AMPK
_doReleaseTRUE
_timestamp2017-02-23 15:16:42
authored[InstanceEdit:5659776] Orlic-Milacic, Marija, 2014-12-23
compartment[Compartment:70101] cytosol
created[InstanceEdit:5631938] Orlic-Milacic, Marija, 2014-10-27
edited[InstanceEdit:5659776] Orlic-Milacic, Marija, 2014-12-23
input[CandidateSet:5629191] SESN1,2,3 [cytosol] [Homo sapiens]
[Complex:380931] p-AMPK heterotrimer:AMP [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5631940] p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
[LiteratureReference:5632356] p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage
[LiteratureReference:8855995] Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells
modified[InstanceEdit:5632357] Orlic-Milacic, Marija, 2014-10-28
[InstanceEdit:5662797] Orlic-Milacic, Marija, 2015-01-13
[InstanceEdit:5662805] Orlic-Milacic, Marija, 2015-01-13
[InstanceEdit:5662823] Orlic-Milacic, Marija, 2015-01-13
[InstanceEdit:5674607] Orlic-Milacic, Marija, 2015-02-13
[InstanceEdit:8855999] Orlic-Milacic, Marija, 2016-02-08
[InstanceEdit:8979246] Orlic-Milacic, Marija, 2017-02-23
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSESN1,2,3 bind AMPK
output[Complex:5631939] SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] [Homo sapiens]
precedingEvent
releaseDate2015-03-19
releaseStatusUPDATED
reviewed[InstanceEdit:5662800] Hwang, Paul M, 2014-12-30
[InstanceEdit:5662803] Kang, Ju-Gyeong, 2014-12-30
[InstanceEdit:5662801] Wang, Ping-yuan, 2014-12-30
[InstanceEdit:8855680] Inga, Alberto, 2016-02-04
[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5679712] R-HSA-5631941.4
summation[Summation:5632350] SESN1, SESN2 and possibly SESN3 are able to bind the AMPK co...
(hasEvent)[Pathway:5628897] TP53 Regulates Metabolic Genes [Homo sapiens]
(updatedInstance)[_UpdateTracker:9783405] Update Tracker - [Reaction:5631941] SESN1,2,3 bind AMPK - v56:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by SESN1,2,3 bind AMPK (5631941)