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Details on Person MeR-Piwil4:piRNA:Tdrd9:Mael:Tdrkh [cytosol]

Class:Id	Complex:5629215
_displayName	MeR-Piwil4:piRNA:Tdrd9:Mael:Tdrkh [cytosol]
_timestamp	2014-11-20 03:11:56
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5629235] May, Bruce, 2014-10-25
hasComponent	[EntityWithAccessionedSequence:5605259] Tdrd9 [cytosol] [Mus musculus] [EntityWithAccessionedSequence:5605396] Mael [cytosol] [Mus musculus] [EntityWithAccessionedSequence:5608259] Tdrkh [cytosol] [Mus musculus] [Complex:5629227] MeR-Piwil4:piRNA [cytosol] [Mus musculus] [EntityWithAccessionedSequence:5605257] MeR-Piwil4 [cytosol] [Mus musculus] [GenomeEncodedEntity:5629220] piRNA [cytosol] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:5608261] Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline [LiteratureReference:5606208] The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline [LiteratureReference:5605232] Cytoplasmic compartmentalization of the fetal piRNA pathway in mice
modified	[InstanceEdit:5637447] May, Bruce, 2014-11-10
name	MeR-Piwil4:piRNA:Tdrd9:Mael:Tdrkh
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:5645804] R-MMU-5629215.1
(inferredFrom)	[Complex:5629214] MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH [cytosol] [Homo sapiens]
(input)	[Reaction:5629230] Henmt1 methylates 2' hydroxyl at 3' end of piRNA in MeR-Piwil4:piRNA:Tdrd9:Mael:Tdrkh [Mus musculus]
(output)	[BlackBoxEvent:5606210] Unknown nuclease cleaves cleaved transposon RNA in MeR-Piwil4:cleaved transposon RNA:Tdrd9:Mael:Tdrkh [Mus musculus]
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No pathways have been reviewed or authored by MeR-Piwil4:piRNA:Tdrd9:Mael:Tdrkh [cytosol] (5629215)