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Details on Person IQGAPs bind CALM1

Class:Id	Reaction:5626549
_displayName	IQGAPs bind CALM1
_doRelease	TRUE
_timestamp	2017-12-06 20:43:34
authored	[InstanceEdit:5628889] Orlic-Milacic, Marija, 2014-10-24 [InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5626552] Orlic-Milacic, Marija, 2014-10-10
edited	[InstanceEdit:5671747] Orlic-Milacic, Marija, 2015-02-02
input	[Complex:5626465] RAC1,CDC42:GTP:IQGAPs [plasma membrane] [Homo sapiens] [Complex:534997] CALM1:4Ca2+ [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5626563] A calcium-dependent interaction between calmodulin and the calponin homology domain of human IQGAP1 [LiteratureReference:5626565] IQ-motif selectivity in human IQGAP2 and IQGAP3: binding of calmodulin and myosin essential light chain [LiteratureReference:5626541] IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments [LiteratureReference:5626515] The IQGAP1 protein is a calmodulin-regulated barbed end capper of actin filaments: possible implications in its function in cell migration
modified	[InstanceEdit:5626556] Orlic-Milacic, Marija, 2014-10-10 [InstanceEdit:5626570] Orlic-Milacic, Marija, 2014-10-10 [InstanceEdit:5627007] Orlic-Milacic, Marija, 2014-10-14 [InstanceEdit:5627791] Orlic-Milacic, Marija, 2014-10-21 [InstanceEdit:5632358] Jassal, Bijay, 2014-10-28 [InstanceEdit:5632370] Jassal, Bijay, 2014-10-28 [InstanceEdit:5643681] Orlic-Milacic, Marija, 2014-11-17 [InstanceEdit:5674244] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674558] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:9032152] Orlic-Milacic, Marija, 2017-12-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IQGAPs bind CALM1
output	[Complex:5626551] RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:5626469] GTP-bound RAC1 and CDC42 bind IQGAPs [Homo sapiens] [Reaction:8848618] Activation of RAC1 by the PXN:CRK complex [Homo sapiens]
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5680091] R-HSA-5626549.3
summation	[Summation:5626554] IQGAP proteins IQGAP1, IQGAP2 and IQGAP3 possess IQ repeats ...
systematicName	Complexed IQGAPs bind CALM1:4Ca2+
(hasEvent)	[Pathway:5626467] RHO GTPases activate IQGAPs [Homo sapiens]
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No pathways have been reviewed or authored by IQGAPs bind CALM1 (5626549)