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Details on Person The IQGAP1 protein is a calmodulin-regulated barbed end capper of actin filaments: possible implications in its function in cell migration

Class:Id	LiteratureReference:5626515
_displayName	The IQGAP1 protein is a calmodulin-regulated barbed end capper of actin filaments: possible implications in its function in cell migration
_timestamp	2014-10-10 15:56:23
author	[Person:5626494] Pelikan-Conchaudron, Andrea [Person:5626498] Le Clainche, Christophe [Person:5626504] Didry, Dominique [Person:5626506] Carlier, Marie-France
created	[InstanceEdit:5626497] Orlic-Milacic, Marija, 2014-10-10
journal	J. Biol. Chem.
pages	35119-28
pubMedIdentifier	21730051
title	The IQGAP1 protein is a calmodulin-regulated barbed end capper of actin filaments: possible implications in its function in cell migration
volume	286
year	2011
(literatureReference)	[Complex:5626510] RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] [Homo sapiens] [RegulationReference:9642519] Negative regulation by 'RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane]' The IQGAP1 protein is a calmodulin-regulated barbed end capper of actin filaments: possible implications in its function in cell migration [Pathway:194315] Signaling by Rho GTPases [Homo sapiens] [Pathway:195258] RHO GTPase Effectors [Homo sapiens] [Pathway:5626467] RHO GTPases activate IQGAPs [Homo sapiens] [Reaction:5626469] GTP-bound RAC1 and CDC42 bind IQGAPs [Homo sapiens] [Reaction:5626507] IQGAPs bind F-actin, which is inhibited by calmodulin [Homo sapiens] [Reaction:5626549] IQGAPs bind CALM1 [Homo sapiens] [Reaction:9013145] RAC1 binds effectors at the plasma membrane [Homo sapiens]
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