Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters

Class:Id	Reaction:5625870
_displayName	KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters
_doRelease	TRUE
_timestamp	2015-03-04 04:21:18
authored	[InstanceEdit:5628889] Orlic-Milacic, Marija, 2014-10-24 [InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
catalystActivity	[CatalystActivity:5625869] histone demethylase activity of p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9643706] histone demethylase activity of p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5625873] Orlic-Milacic, Marija, 2014-10-08
edited	[InstanceEdit:5628889] Orlic-Milacic, Marija, 2014-10-24
input	[Complex:5625863] p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] [Homo sapiens] [SimpleEntity:113685] O2 [nucleoplasm] [SimpleEntity:113671] 2OG [nucleoplasm]
isChimeric	FALSE
literatureReference	[LiteratureReference:5625775] Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation [LiteratureReference:4687010] LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription
modified	[InstanceEdit:5627007] Orlic-Milacic, Marija, 2014-10-14 [InstanceEdit:5627791] Orlic-Milacic, Marija, 2014-10-21 [InstanceEdit:5632358] Jassal, Bijay, 2014-10-28 [InstanceEdit:5643681] Orlic-Milacic, Marija, 2014-11-17 [InstanceEdit:5674244] Orlic-Milacic, Marija, 2015-02-11 [InstanceEdit:5674555] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:5678309] Orlic-Milacic, Marija, 2015-02-23 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters
output	[SimpleEntity:159942] CO2 [nucleoplasm] [SimpleEntity:29478] CH2O [nucleoplasm] [SimpleEntity:159939] SUCCA [nucleoplasm] [EntityWithAccessionedSequence:996769] KDM1A [nucleoplasm] [Homo sapiens] [Complex:5625874] p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:5625848] KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters [Homo sapiens] [Reaction:5625849] Demethylase KDM1A binds KLK2 and KLK3 promoters [Homo sapiens]
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5680346] R-HSA-5625870.3
summation	[Summation:5625877] PKN1-mediated phosphorylation of histone H3 threonine residu...
systematicName	Complexed KDM1A demethylates complexed p-T12,MeK-10-H3
(hasEvent)	[Pathway:5625886] Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:5625883] PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 [Homo sapiens] [NegativePrecedingEvent:9864364] Futile Cycle: KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters
[Change default viewing format]

No pathways have been reviewed or authored by KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (5625870)