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Details on Person histone demethylase activity of p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm]

Class:IdCatalystActivity:5625869
_displayNamehistone demethylase activity of p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm]
_timestamp2014-10-08 15:46:45
activeUnit[EntityWithAccessionedSequence:996769] KDM1A [nucleoplasm] [Homo sapiens]
activity[GO_MolecularFunction:259643] histone demethylase activity
created[InstanceEdit:5625873] Orlic-Milacic, Marija, 2014-10-08
modified[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9689079] Cook, Justin, 2020-05-15
[InstanceEdit:9689079] Cook, Justin, 2020-05-15
physicalEntity[Complex:5625863] p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] [Homo sapiens]
(catalystActivity)[CatalystActivityReference:9643706] histone demethylase activity of p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation
[Reaction:5625870] KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters [Homo sapiens]
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No pathways have been reviewed or authored by histone demethylase activity of p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (5625869)
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