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Details on Person INPP5E translocates to the primary cilium

Class:Id	BlackBoxEvent:5624954
_displayName	INPP5E translocates to the primary cilium
_doRelease	TRUE
_timestamp	2016-11-06 23:53:01
authored	[InstanceEdit:5624166] Rothfels, Karen, 2014-09-19
compartment	[Compartment:18730] cilium
created	[InstanceEdit:5624955] Rothfels, Karen, 2014-09-30
edited	[InstanceEdit:5626894] Jassal, Bijay, 2014-10-13
input	[Complex:5624934] PDE6D:INPP5E [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5624816] INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse [LiteratureReference:1675802] Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies [LiteratureReference:5624801] ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting
modified	[InstanceEdit:5625174] D'Eustachio, Peter, 2014-10-02 [InstanceEdit:5627029] Rothfels, Karen, 2014-10-14 [InstanceEdit:5627214] Rothfels, Karen, 2014-10-16 [InstanceEdit:5627640] Rothfels, Karen, 2014-10-20 [InstanceEdit:5632708] Matthews, Lisa, 2014-10-28 [InstanceEdit:5638037] Rothfels, Karen, 2014-11-13 [InstanceEdit:5638409] Rothfels, Karen, 2014-11-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	INPP5E translocates to the primary cilium
output	[Complex:5624936] PDE6D:INPP5E [cilium] [Homo sapiens]
precedingEvent	[Reaction:5624956] PDE6D binds INPP5E [Homo sapiens]
releaseDate	2014-12-11
reviewed	[InstanceEdit:5637996] Lorentzen, Esben, 2014-11-10 [InstanceEdit:5638370] Goncalves, Joao, 2014-11-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5645014] R-HSA-5624954.2
summation	[Summation:5624841] INPP5E is a ciliary peripheral membrane protein that is asso...
systematicName	PDE6D:INPP5E translocates from cytosol to primary cilium
(hasEvent)	[Pathway:5624958] ARL13B-mediated ciliary trafficking of INPP5E [Homo sapiens]
(precedingEvent)	[Reaction:5624953] ARL13B binds INPP5E [Homo sapiens]
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