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Details on Person Assembly of the anterograde IFT train

Class:Id	Reaction:5624949
_displayName	Assembly of the anterograde IFT train
_doRelease	TRUE
_timestamp	2016-11-06 23:53:01
authored	[InstanceEdit:5624166] Rothfels, Karen, 2014-09-19
compartment	[Compartment:18730] cilium
created	[InstanceEdit:5624950] Rothfels, Karen, 2014-09-30
edited	[InstanceEdit:5626894] Jassal, Bijay, 2014-10-13
input	[Complex:5617795] IFT A [cilium] [Homo sapiens] [Complex:5617799] IFT B [cilium] [Homo sapiens] [Complex:5624940] dynein-2 [cilium] [Homo sapiens] [Complex:5624943] active kinesin-2 motors [cilium] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5625436] A motility in the eukaryotic flagellum unrelated to flagellar beating [LiteratureReference:5625473] The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane [LiteratureReference:5625465] Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling [LiteratureReference:5617758] Transport of a novel complex in the cytoplasmic matrix of Chlamydomonas flagella [LiteratureReference:5617540] Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons [LiteratureReference:5618172] The roles of evolutionarily conserved functional modules in cilia-related trafficking [LiteratureReference:5625455] Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans [LiteratureReference:5625477] Two anterograde intraflagellar transport motors cooperate to build sensory cilia on C. elegans neurons [LiteratureReference:5624813] Functional coordination of intraflagellar transport motors [LiteratureReference:5623296] Ciliary targeting of olfactory CNG channels requires the CNGB1b subunit and the kinesin-2 motor protein, KIF17 [LiteratureReference:5624809] Different roles for KIF17 and kinesin II in photoreceptor development and maintenance [LiteratureReference:5624836] The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment development [LiteratureReference:5624805] Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP [LiteratureReference:5624824] Kinesin motors and primary cilia [LiteratureReference:5625472] The BBSome controls IFT assembly and turnaround in cilia [LiteratureReference:5624826] Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport [LiteratureReference:5617505] A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis [LiteratureReference:5624017] The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis [LiteratureReference:5637915] Electron-tomographic analysis of intraflagellar transport particle trains in situ
modified	[InstanceEdit:5625174] D'Eustachio, Peter, 2014-10-02 [InstanceEdit:5625479] Rothfels, Karen, 2014-10-03 [InstanceEdit:5627053] Rothfels, Karen, 2014-10-14 [InstanceEdit:5627201] Rothfels, Karen, 2014-10-16 [InstanceEdit:5627627] Rothfels, Karen, 2014-10-20 [InstanceEdit:5633212] Matthews, Lisa, 2014-10-31 [InstanceEdit:5638053] Rothfels, Karen, 2014-11-13 [InstanceEdit:5638390] Rothfels, Karen, 2014-11-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Assembly of the anterograde IFT train
output	[Complex:5624945] anterograde IFT trains [cilium] [Homo sapiens]
releaseDate	2014-12-11
reviewed	[InstanceEdit:5637996] Lorentzen, Esben, 2014-11-10 [InstanceEdit:5638370] Goncalves, Joao, 2014-11-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6781699] R-HSA-5624949.2
summation	[Summation:5625462] IFT particles were first characterized in Chlamydomonas rein...
systematicName	IFT A, IFT B, dynein-2, active kinesin-2 motors bind forming anterograde IFT trains
(hasEvent)	[Pathway:5620924] Intraflagellar transport [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:5625416] Anterograde IFT [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9782415] Update Tracker - [Reaction:5624949] Assembly of the anterograde IFT train - v59:[modifyText]
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