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Details on Person SFKs phosphorylates RAF1 on Y340,Y341

Class:Id	BlackBoxEvent:5624486
_displayName	SFKs phosphorylates RAF1 on Y340,Y341
_doRelease	TRUE
_timestamp	2015-03-04 03:56:54
authored	[InstanceEdit:5660664] Garapati, P V, 2015-01-04
catalystActivity	[CatalystActivity:5621374] protein tyrosine kinase activity of FYN, LYN [cytosol]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:5624475] Garapati, P V, 2014-09-29
edited	[InstanceEdit:5660664] Garapati, P V, 2015-01-04
input	[Complex:5624470] p21 RAS:GTP:p-S338-RAF1 [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5624485] DC-SIGN ligation on dendritic cells results in ERK and PI3K activation and modulates cytokine production [LiteratureReference:5624471] C-type lectin DC-SIGN: an adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity
modified	[InstanceEdit:5674204] Garapati, P V, 2015-02-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SFKs phosphorylates RAF1 on Y340,Y341
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [Complex:5624477] p21 RAS:GTP:p-S338,Y340,Y341-RAF1 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:5624492] PAK phosphorylates p21 RAF1 on S338 [Homo sapiens] [Reaction:5624494] RAF1 binds p21 RAS:GTP [Homo sapiens]
releaseDate	2015-03-19
reviewed	[InstanceEdit:5621625] Geijtenbeek, Teunis B H, 2014-09-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5679922] R-HSA-5624486.2
summation	[Summation:5624483] Phosphorylation of tyrosine 340, 341 (Y340,341) on RAF1 in r...
(hasEvent)	[Pathway:5621575] CD209 (DC-SIGN) signaling [Homo sapiens]
(precedingEvent)	[Reaction:5624473] Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit [Homo sapiens]
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No pathways have been reviewed or authored by SFKs phosphorylates RAF1 on Y340,Y341 (5624486)