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Details on Person An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium
| Class:Id | LiteratureReference:5623984 |
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| _displayName | An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium |
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| _timestamp | 2014-09-19 18:07:18 |
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| author | [Person:5623266] Wright, Kevin J
[Person:5623071] Baye, Lisa M
[Person:5623924] Olivier-Mason, Anique
[Person:5610182] Mukhopadhyay, Saikat
[Person:5623933] Sang, Liyun
[Person:5623898] Kwong, Mandy
[Person:2399703] Wang, Weiru
[Person:5623926] Pretorius, Pamela R
[Person:4416516] Sheffield, Val C
[Person:5617562] Sengupta, Piali
[Person:3965162] Slusarski, Diane C
[Person:5609712] Jackson, Peter K |
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| created | [InstanceEdit:5623985] Rothfels, Karen, 2014-09-19 |
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| journal | Genes Dev. |
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| pages | 2347-60 |
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| pubMedIdentifier | 22085962 |
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| title | An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium |
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| volume | 25 |
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| year | 2011 |
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| (literatureReference) | [Pathway:5620920] Cargo trafficking to the periciliary membrane [Homo sapiens]
[Reaction:5624130] Myristoylated NPHP3 translocates into the ciliary membrane [Homo sapiens]
[Reaction:5624131] UNC119B binds myristoylated proteins [Homo sapiens]
[BlackBoxEvent:5624132] UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium [Homo sapiens]
[Reaction:5624133] ARL3:GTP binds the UNC119B complex [Homo sapiens]
[Reaction:5624134] ARL3-mediated hydrolysis of GTP releases UNC119B [Homo sapiens]
[Pathway:5624138] Trafficking of myristoylated proteins to the cilium [Homo sapiens]
[Reaction:5638004] RP2 binds ARL3:GTP:UNC119B [Homo sapiens]
[Reaction:5638006] ARL3 hydrolyzes GTP [Homo sapiens]
[Reaction:5638007] RP2 activates the GTPase activity of ARL3 [Homo sapiens] |
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