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Details on Person Cargo-carrying vesicles bud from the TGN

Class:Id	BlackBoxEvent:5623525
_displayName	Cargo-carrying vesicles bud from the TGN
_doRelease	TRUE
_timestamp	2014-11-20 02:37:06
authored	[InstanceEdit:5620934] Rothfels, Karen, 2014-08-27
compartment	[Compartment:13949] Golgi-associated vesicle membrane
created	[InstanceEdit:5623523] Rothfels, Karen, 2014-09-12
edited	[InstanceEdit:5626894] Jassal, Bijay, 2014-10-13
input	[Complex:5623447] RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5623279] A BAR domain in the N terminus of the Arf GAP ASAP1 affects membrane structure and trafficking of epidermal growth factor receptor [LiteratureReference:5623292] Autoinhibition of Arf GTPase-activating protein activity by the BAR domain in ASAP1 [LiteratureReference:5623326] Structural characteristics of BAR domain superfamily to sculpt the membrane [LiteratureReference:5623289] Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome [LiteratureReference:5623294] Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4 [LiteratureReference:5623300] Crosstalk of Arf and Rab GTPases en route to cilia
modified	[InstanceEdit:5627026] Rothfels, Karen, 2014-10-14 [InstanceEdit:5627209] Rothfels, Karen, 2014-10-16 [InstanceEdit:5627636] Rothfels, Karen, 2014-10-20 [InstanceEdit:5638062] Rothfels, Karen, 2014-11-13 [InstanceEdit:5638403] Rothfels, Karen, 2014-11-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Cargo-carrying vesicles bud from the TGN
output	[Complex:5623450] RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] [Homo sapiens]
precedingEvent	[Reaction:5623521] RAB3IP stimulates nucleotide exchange on RAB8A [Homo sapiens] [Reaction:5623519] RAB3IP and RAB8A bind to the ciliary targeting complex [Homo sapiens]
releaseDate	2014-12-11
reviewed	[InstanceEdit:5637996] Lorentzen, Esben, 2014-11-10 [InstanceEdit:5638370] Goncalves, Joao, 2014-11-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644421] R-HSA-5623525.2
summation	[Summation:5623350] Membrane budding at the trans-Golgi network is promoted at l...
(hasEvent)	[Pathway:5620916] VxPx cargo-targeting to cilium [Homo sapiens]
(precedingEvent)	[Reaction:5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex [Homo sapiens]
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No pathways have been reviewed or authored by Cargo-carrying vesicles bud from the TGN (5623525)