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Details on Person CLEC4C binds HIV and HCV glycoproteins

Class:Id	Reaction:5621371
_displayName	CLEC4C binds HIV and HCV glycoproteins
_doRelease	TRUE
_timestamp	2015-03-04 03:49:19
authored	[InstanceEdit:5621373] Garapati, P V, 2014-08-29 [InstanceEdit:5621479] Garapati, P V, 2014-08-29
compartment	[Compartment:876] plasma membrane [Compartment:171242] viral envelope
created	[InstanceEdit:5621373] Garapati, P V, 2014-08-29
edited	[InstanceEdit:5621479] Garapati, P V, 2014-08-29
input	[Complex:5621153] CLEC4C:FCER1G dimer [plasma membrane] [Homo sapiens] [DefinedSet:5621134] HIV gp120,HCV gp E2 [viral envelope] [Hepatitis C virus genotype 2a]
isChimeric	FALSE
literatureReference	[LiteratureReference:5621210] HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells [LiteratureReference:5621243] Human C-type lectin domain family 4, member C (CLEC4C/BDCA-2/CD303) is a receptor for asialo-galactosyl-oligosaccharides
modified	[InstanceEdit:5663074] Garapati, P V, 2015-01-15 [InstanceEdit:5671870] Garapati, P V, 2015-02-03 [InstanceEdit:5674203] Garapati, P V, 2015-02-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CLEC4C binds HIV and HCV glycoproteins
output	[Complex:5621155] CLEC4C:FCER1G dimer:HIV gp120,HCV gp E2 [plasma membrane] [Homo sapiens]
relatedSpecies	[Species:5621126] Hepatitis C virus genotype 2a [Species:164493] Human immunodeficiency virus 1
releaseDate	2015-03-19
reviewed	[InstanceEdit:5621625] Geijtenbeek, Teunis B H, 2014-09-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5679796] R-HSA-5621371.2
summation	[Summation:5621368] CLEC4C (C-type lectin domain family 4 member C/Blood dendrit...
(hasEvent)	[Pathway:5621480] Dectin-2 family [Homo sapiens]
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No pathways have been reviewed or authored by CLEC4C binds HIV and HCV glycoproteins (5621371)