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Details on Person Hoxb2 gene is transcribed
Class:Id BlackBoxEvent:5619432
_displayName Hoxb2 gene is transcribed
_doRelease TRUE
_timestamp 2015-11-20 15:12:02
authored [InstanceEdit:5618010] May, Bruce, 2014-08-16 [InstanceEdit:6810137] Rezsohazy, René, 2015-11-15
compartment [Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created [InstanceEdit:5619416] May, Bruce, 2014-08-22
edited [InstanceEdit:5618010] May, Bruce, 2014-08-16
input [EntityWithAccessionedSequence:5619364] Hoxb2 gene [nucleoplasm] [Mus musculus]
isChimeric FALSE
literatureReference [LiteratureReference:5619164] Induction of HoxB transcription by retinoic acid requires actin polymerization [LiteratureReference:5619296] Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interactions between Prep1, Pbx and Hox proteins [LiteratureReference:5619174] Differences in Krox20-dependent regulation of Hoxa2 and Hoxb2 during hindbrain development [LiteratureReference:5619193] Hoxb-2 transcriptional activation in rhombomeres 3 and 5 requires an evolutionarily conserved cis-acting element in addition to the Krox-20 binding site [LiteratureReference:5619325] The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation [LiteratureReference:5619270] Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity [LiteratureReference:5619299] Cross-regulation in the mouse HoxB complex: the expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1 [LiteratureReference:5689990] A yeast artificial chromosome containing the mouse homeobox cluster Hox-2
modified [InstanceEdit:5621717] May, Bruce, 2014-09-03 [InstanceEdit:5634097] May, Bruce, 2014-11-03 [InstanceEdit:5690006] May, Bruce, 2015-04-27 [InstanceEdit:5693645] May, Bruce, 2015-05-17 [InstanceEdit:6808659] May, Bruce, 2015-11-08 [InstanceEdit:6810141] May, Bruce, 2015-11-15 [InstanceEdit:6810171] May, Bruce, 2015-11-15 [InstanceEdit:6810187] May, Bruce, 2015-11-16 [InstanceEdit:6810603] Matthews, Lisa, 2015-11-18 [InstanceEdit:6810604] Matthews, Lisa, 2015-11-18 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Hoxb2 gene is transcribed
output [EntityWithAccessionedSequence:5619339] Hoxb2 mRNA [cytosol] [Mus musculus]
precedingEvent
regulatedBy [PositiveRegulation:5634083] Positive regulation by 'Egr2 at active Hoxb2 chromatin [nucleoplasm]' [PositiveRegulation:5634089] Positive regulation by 'Hoxb1:Pbx1:Meis1 at active Hoxb2 chromatin [nucleoplasm]'
regulationReference [RegulationReference:9642110] Positive regulation by 'Hoxb1:Pbx1:Meis1 at active Hoxb2 chromatin [nucleoplasm]' Cross-regulation in the mouse HoxB complex: the expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1 [RegulationReference:9642806] Positive regulation by 'Egr2 at active Hoxb2 chromatin [nucleoplasm]' Differences in Krox20-dependent regulation of Hoxa2 and Hoxb2 during hindbrain development
releaseDate 2015-12-15
releaseStatus NEW
reviewed [InstanceEdit:5693642] Blasi, F, 2015-05-13
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48892] Mus musculus
stableIdentifier [StableIdentifier:6812593] R-MMU-5619432.4
summation [Summation:5621695] The Hoxb2 gene is transcribed to yield mRNA (Rubock et al. 1...
(inferredFrom) [BlackBoxEvent:5617486] HOXB2 gene is transcribed [Homo sapiens]
(precedingEvent) [BlackBoxEvent:5619431] Hoxb2 mRNA is translated [Mus musculus]
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