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Details on Person UniProt:Q9VLN1 Wdr82

Class:IdReferenceGeneProduct:5618417
_chainChangeLogchain:1-317 added on Sat February 7 2015
_displayNameUniProt:Q9VLN1 Wdr82
_timestamp2023-11-03 17:36:07
chainchain:1-317
checksumFAE08A606ED23CAD
commentFUNCTION Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 (PubMed:21694722, PubMed:21875999). Together with su(sable), part of a transcription termination checkpoint that promotes transcription termination of aberrant RNAs and their subsequent degradation by the nuclear exosome (PubMed:26577379).SUBUNIT Component of the SET1 complex, composed at least of the catalytic subunit Set1, wds/WDR5, Wdr82, Rbbp5, ash2, Cfp1/CXXC1, hcf and Dpy-30L1 (PubMed:21694722, PubMed:21875999). Interacts with male-specific lethal (MSL) histone acetyltransferase complex at least composed of mof, msl-1, msl-2 and msl-3 (PubMed:23295261). Interacts with su(sable) (PubMed:26577379).SUBCELLULAR LOCATION Belongs to the WD repeat SWD2 family.
created[InstanceEdit:5618415] Weiser, JD
descriptionrecommendedName: fullName evidence="1"WD repeat-containing protein 82
geneNameWdr82
CG17293
identifierQ9VLN1
isSequenceChangedFALSE
keywordNucleus
Reference proteome
Repeat
Transcription
Transcription regulation
Transcription termination
WD repeat
modified[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9657908] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9796772] Weiser, Joel
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameWdr82
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierWDR82_DROME
sequenceLength317
species[Species:56210] Drosophila melanogaster
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No pathways have been reviewed or authored by UniProt:Q9VLN1 Wdr82 (5618417)