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Details on Person Requirement of Smurf-mediated endocytosis of Patched1 in Sonic Hedgehog signal reception
| Class:Id | LiteratureReference:5618035 |
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| _displayName | Requirement of Smurf-mediated endocytosis of Patched1 in Sonic Hedgehog signal reception |
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| _timestamp | 2014-08-18 15:30:15 |
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| author | [Person:5618029] Yue, Shen
[Person:2176442] Tang, LY
[Person:5618018] Tang, Ying
[Person:2176455] Tang, Y
[Person:5618025] Shen, Qiu-Hong
[Person:5618033] Ding, Jie
[Person:2395358] Chen, Yan
[Person:5618034] Zhang, Zengdi
[Person:5618036] Yu, Ting-Ting
[Person:5618027] Zhang, Ying E
[Person:2176448] Cheng, SY |
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| created | [InstanceEdit:5618030] Rothfels, Karen, 2014-08-18 |
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| journal | Elife |
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| modified | [InstanceEdit:5618048] Rothfels, Karen, 2014-08-18 |
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| pages | e02555 |
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| pubMedIdentifier | 24925320 |
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| title | Requirement of Smurf-mediated endocytosis of Patched1 in Sonic Hedgehog signal reception |
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| year | 2014 |
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| (literatureReference) | [BlackBoxEvent:5610763] PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal [Homo sapiens]
[Reaction:5632642] Smurf1/2 bind Ptch1 [Mus musculus]
[Reaction:5632644] Smurf1/2 ubiquitinates Ptch1 [Mus musculus]
[Reaction:5632646] SMURF1/2 bind PTCH1 [Homo sapiens]
[Reaction:5632648] SMURF1/2 ubiquitinates PTCH1 [Homo sapiens]
[Reaction:5632672] ADRBK1 phosphorylates SMO dimer [Homo sapiens]
[BlackBoxEvent:5632675] Ptch is internalized [Mus musculus]
[BlackBoxEvent:5632677] PTCH is internalized [Homo sapiens]
[Reaction:5635865] SMURF1/2 dissociates from ub-PTCH1 [Homo sapiens] |
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