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Details on Person RARA,B:RXRA at HOXD4 bivalent chromatin [nucleoplasm]

Class:Id	Complex:5617895
_displayName	RARA,B:RXRA at HOXD4 bivalent chromatin [nucleoplasm]
_timestamp	2015-11-20 15:04:50
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5617850] May, Bruce, 2014-08-15
hasComponent	[Complex:5617447] Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] [Homo sapiens] [DefinedSet:212266] Histone H3 (H3K27me3) [nucleoplasm] [Homo sapiens] [DefinedSet:1214232] Histone H3 (H3K4me3) [nucleoplasm] [Homo sapiens] [CandidateSet:181899] Histone H2A [nucleoplasm] [Homo sapiens] [CandidateSet:181899] Histone H2A [nucleoplasm] [Homo sapiens] [CandidateSet:181911] Histone H2B [nucleoplasm] [Homo sapiens] [CandidateSet:181911] Histone H2B [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:181902] HIST1H4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:181902] HIST1H4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:442501] NCOR1 [nucleoplasm] [Homo sapiens] [Complex:212285] PRC2 (EZH2) Core [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:212278] EED [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:212298] EZH2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:212217] SUZ12 [nucleoplasm] [Homo sapiens] [DefinedSet:4839773] RBBP4,7 [nucleoplasm] [Homo sapiens] [Complex:5617865] RARA,B:RXRA [nucleoplasm] [Homo sapiens] [DefinedSet:5617943] RARA,RARB [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:381319] RXRA [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5617853] HOXD4 gene [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:389115] PCGF2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:4086091] YY1 [nucleoplasm] [Homo sapiens]
inferredFrom	[Complex:5619392] Rara,b:Rxra at Hoxd4 bivalent chromatin [nucleoplasm] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:5619459] In vitro and transgenic analysis of a human HOXD4 retinoid-responsive enhancer [LiteratureReference:5619449] Regulation of the human HOXD4 gene by retinoids [LiteratureReference:5619306] HOXD4 and regulation of the group 4 paralog genes [LiteratureReference:4687099] A histone H3 lysine 27 demethylase regulates animal posterior development [LiteratureReference:5619280] Functional dissection of HOXD cluster genes in regulation of neuroblastoma cell proliferation and differentiation [LiteratureReference:5687948] Recruitment of nuclear receptor corepressor and coactivator to the retinoic acid receptor by retinoid ligands. Influence of DNA-heterodimer interactions
modified	[InstanceEdit:5618010] May, Bruce, 2014-08-16 [InstanceEdit:5619473] May, Bruce, 2014-08-22 [InstanceEdit:6810175] May, Bruce, 2015-11-16
name	RARA,B:RXRA at HOXD4 bivalent chromatin
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812026] R-HSA-5617895.1
(input)	[BlackBoxEvent:5617896] Retinoic acid activates HOXD4 chromatin [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9894672] Update Tracker - [Complex:5617895] RARA,B:RXRA at HOXD4 bivalent chromatin [nucleoplasm] - v57:[updateContainedComponent] [_UpdateTracker:9904443] Update Tracker - [Complex:5617895] RARA,B:RXRA at HOXD4 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
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No pathways have been reviewed or authored by RARA,B:RXRA at HOXD4 bivalent chromatin [nucleoplasm] (5617895)