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Details on Person RARA,B:RXRA at HOXA4 bivalent chromatin [nucleoplasm]

Class:Id	Complex:5617876
_displayName	RARA,B:RXRA at HOXA4 bivalent chromatin [nucleoplasm]
_timestamp	2015-11-20 15:04:47
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5617850] May, Bruce, 2014-08-15
hasComponent	[Complex:5617447] Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] [Homo sapiens] [DefinedSet:212266] Histone H3 (H3K27me3) [nucleoplasm] [Homo sapiens] [DefinedSet:1214232] Histone H3 (H3K4me3) [nucleoplasm] [Homo sapiens] [CandidateSet:181899] Histone H2A [nucleoplasm] [Homo sapiens] [CandidateSet:181899] Histone H2A [nucleoplasm] [Homo sapiens] [CandidateSet:181911] Histone H2B [nucleoplasm] [Homo sapiens] [CandidateSet:181911] Histone H2B [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:181902] HIST1H4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:181902] HIST1H4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:442501] NCOR1 [nucleoplasm] [Homo sapiens] [Complex:212285] PRC2 (EZH2) Core [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:212278] EED [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:212298] EZH2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:212217] SUZ12 [nucleoplasm] [Homo sapiens] [DefinedSet:4839773] RBBP4,7 [nucleoplasm] [Homo sapiens] [Complex:5617865] RARA,B:RXRA [nucleoplasm] [Homo sapiens] [DefinedSet:5617943] RARA,RARB [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:381319] RXRA [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5617875] HOXA4 gene [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:3782562] CTCF [nucleoplasm] [Homo sapiens]
inferredFrom	[Complex:5619338] Rara,b:Rxra at Hoxa4 bivalent chromatin [nucleoplasm] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:5624425] CTCF Controls HOXA Cluster Silencing and Mediates PRC2-Repressive Higher-Order Chromatin Structure in NT2/D1 Cells [LiteratureReference:4687099] A histone H3 lysine 27 demethylase regulates animal posterior development [LiteratureReference:5619159] Functional interaction between a RARE and an AP-2 binding site in the regulation of the human HOX A4 gene promoter [LiteratureReference:5620950] Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster
modified	[InstanceEdit:5618010] May, Bruce, 2014-08-16 [InstanceEdit:5626881] May, Bruce, 2014-10-11 [InstanceEdit:6810175] May, Bruce, 2015-11-16
name	RARA,B:RXRA at HOXA4 bivalent chromatin
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812021] R-HSA-5617876.1
(input)	[BlackBoxEvent:5617862] Retinoic acid activates HOXA4 chromatin [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9894530] Update Tracker - [Complex:5617876] RARA,B:RXRA at HOXA4 bivalent chromatin [nucleoplasm] - v57:[updateContainedComponent] [_UpdateTracker:9904632] Update Tracker - [Complex:5617876] RARA,B:RXRA at HOXA4 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
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No pathways have been reviewed or authored by RARA,B:RXRA at HOXA4 bivalent chromatin [nucleoplasm] (5617876)