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Details on Person Retinoic acid activates HOXA4 chromatin

Class:IdBlackBoxEvent:5617862
_displayNameRetinoic acid activates HOXA4 chromatin
_doReleaseTRUE
_timestamp2015-11-20 15:11:36
authored[InstanceEdit:5617432] May, Bruce, 2014-08-07
[InstanceEdit:6810137] Rezsohazy, René, 2015-11-15
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5617850] May, Bruce, 2014-08-15
edited[InstanceEdit:5617678] May, Bruce, 2014-08-13
inferredFrom
input[Complex:5617876] RARA,B:RXRA at HOXA4 bivalent chromatin [nucleoplasm] [Homo sapiens]
[SimpleEntity:5334804] atRA [nucleoplasm]
[Complex:209680] RNA Polymerase II holoenzyme complex (generic) [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:442488] NCOA3 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:381325] EP300 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5619159] Functional interaction between a RARE and an AP-2 binding site in the regulation of the human HOX A4 gene promoter
[LiteratureReference:4687099] A histone H3 lysine 27 demethylase regulates animal posterior development
[LiteratureReference:5620950] Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster
[LiteratureReference:5626795] Hox in motion: tracking HoxA cluster conformation during differentiation
[LiteratureReference:5624425] CTCF Controls HOXA Cluster Silencing and Mediates PRC2-Repressive Higher-Order Chromatin Structure in NT2/D1 Cells
modified[InstanceEdit:5619442] May, Bruce, 2014-08-22
[InstanceEdit:5620957] May, Bruce, 2014-08-28
[InstanceEdit:5626881] May, Bruce, 2014-10-11
[InstanceEdit:5689927] May, Bruce, 2015-04-25
[InstanceEdit:5693645] May, Bruce, 2015-05-17
[InstanceEdit:6808659] May, Bruce, 2015-11-08
[InstanceEdit:6810141] May, Bruce, 2015-11-15
[InstanceEdit:6810171] May, Bruce, 2015-11-15
[InstanceEdit:6810187] May, Bruce, 2015-11-16
[InstanceEdit:6810603] Matthews, Lisa, 2015-11-18
[InstanceEdit:6810604] Matthews, Lisa, 2015-11-18
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRetinoic acid activates HOXA4 chromatin
output[Complex:5617873] atRA:RARA,B:RXRA at active HOXA4 chromatin [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:442501] NCOR1 [nucleoplasm] [Homo sapiens]
[Complex:212285] PRC2 (EZH2) Core [nucleoplasm] [Homo sapiens]
releaseDate2015-12-15
releaseStatusNEW
reviewed[InstanceEdit:5693642] Blasi, F, 2015-05-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6812558] R-HSA-5617862.2
summation[Summation:5617883] As inferred from mouse embryos, retinoic acid initially acti...
(hasEvent)[Pathway:5617472] Activation of anterior HOX genes in hindbrain development during early embryogenesis [Homo sapiens]
(precedingEvent)[BlackBoxEvent:5617877] HOXA4 gene is transcribed [Homo sapiens]
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No pathways have been reviewed or authored by Retinoic acid activates HOXA4 chromatin (5617862)
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