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Details on Person HOXD1 chromatin is activated
Class:Id BlackBoxEvent:5617445
_displayName HOXD1 chromatin is activated
_doRelease TRUE
_timestamp 2015-11-20 15:11:21
authored [InstanceEdit:5617432] May, Bruce, 2014-08-07 [InstanceEdit:6810137] Rezsohazy, René, 2015-11-15
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:5617463] May, Bruce, 2014-08-08
edited [InstanceEdit:5617425] May, Bruce, 2014-08-01
inferredFrom
input [Complex:209680] RNA Polymerase II holoenzyme complex (generic) [nucleoplasm] [Homo sapiens] [Complex:5617473] HOXD1 bivalent chromatin [nucleoplasm] [Homo sapiens]
isChimeric FALSE
literatureReference [LiteratureReference:5619280] Functional dissection of HOXD cluster genes in regulation of neuroblastoma cell proliferation and differentiation [LiteratureReference:5619215] Up-regulation of HOXC6, HOXD1, and HOXD8 homeobox gene expression in human neuroblastoma cells following chemical induction of differentiation [LiteratureReference:4687099] A histone H3 lysine 27 demethylase regulates animal posterior development
modified [InstanceEdit:5617678] May, Bruce, 2014-08-13 [InstanceEdit:5619442] May, Bruce, 2014-08-22 [InstanceEdit:5620957] May, Bruce, 2014-08-28 [InstanceEdit:5621561] May, Bruce, 2014-08-31 [InstanceEdit:5675636] May, Bruce, 2015-02-16 [InstanceEdit:5693645] May, Bruce, 2015-05-17 [InstanceEdit:6808659] May, Bruce, 2015-11-08 [InstanceEdit:6810141] May, Bruce, 2015-11-15 [InstanceEdit:6810171] May, Bruce, 2015-11-15 [InstanceEdit:6810187] May, Bruce, 2015-11-16 [InstanceEdit:6810603] Matthews, Lisa, 2015-11-18 [InstanceEdit:6810604] Matthews, Lisa, 2015-11-18 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name HOXD1 chromatin is activated
output [Complex:212285] PRC2 (EZH2) Core [nucleoplasm] [Homo sapiens] [Complex:5617453] HOXD1 active chromatin [nucleoplasm] [Homo sapiens]
regulatedBy [PositiveRegulation:5626785] Positive regulation by 'atRA [nucleoplasm]'
regulationReference [RegulationReference:9642557] Positive regulation by 'atRA [nucleoplasm]' Functional dissection of HOXD cluster genes in regulation of neuroblastoma cell proliferation and differentiation
releaseDate 2015-12-15
releaseStatus NEW
reviewed [InstanceEdit:5693642] Blasi, F, 2015-05-13
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:6812533] R-HSA-5617445.4
summation [Summation:5621558] As inferred from the Hoxd1 homolog in mouse embryos, HOXD1 i...
(hasEvent) [Pathway:5617472] Activation of anterior HOX genes in hindbrain development during early embryogenesis [Homo sapiens]
(precedingEvent) [BlackBoxEvent:5617462] HOXD1 gene is transcribed [Homo sapiens]
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