Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person After cleavage by PLD6 at the 5' end, the pre-piRNA is bound...

Class:IdSummation:5615691
_displayNameAfter cleavage by PLD6 at the 5' end, the pre-piRNA is bound...
_timestamp2014-10-25 07:44:57
created[InstanceEdit:5615683] May, Bruce, 2014-07-29
modified[InstanceEdit:5629248] May, Bruce, 2014-10-25
textAfter cleavage by PLD6 at the 5' end, the pre-piRNA is bound by PIWIL1 (HIWI, homolog of MIWI in mouse), likely in a complex with other proteins such as TDRD6 and TDRKH, which interact with methylated arginine residues on PIWIL1 and are required for piRNA biogenesis. Binding by PIWIL1 is believed to be selective for pre-piRNAs that have uracil residues at their 5' ends.
(summation)[Reaction:5615682] Complexed PIWIL1 binds pre-piRNA [Homo sapiens]
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