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Details on Person Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis

Class:IdLiteratureReference:5612485
_displayNameHedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis
_timestamp2014-07-23 19:43:44
author[Person:5612483] Lee, Eunice Y
[Person:5612466] Ji, Hongkai
[Person:5612487] Ouyang, Zhengqing
[Person:5612484] Zhou, Baiyu
[Person:5612486] Ma, Wenxiu
[Person:5612465] Vokes, Steven A
[Person:3238006] McMahon, Andrew P
[Person:5159220] Wong, Wing H
[Person:5358151] Scott, Matthew P
created[InstanceEdit:5612482] Rothfels, Karen, 2014-07-23
journalProc. Natl. Acad. Sci. U.S.A.
pages9736-41
pubMedIdentifier20460306
titleHedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis
volume107
year2010
(literatureReference)[Reaction:5612508] GLI3R binds the PTCH1 promoter [Homo sapiens]
[BlackBoxEvent:5612510] Expression of PTCH1 is repressed by GLI3R in the absence of Hh signaling [Homo sapiens]
[BlackBoxEvent:5635841] GLI proteins are phosphorylated [Homo sapiens]
[Reaction:5635846] GLI proteins bind GLI1 gene [Homo sapiens]
[Reaction:5635848] GLI proteins bind PTCH1 gene [Homo sapiens]
[Reaction:5635850] GLI1 binds HHIP gene, PTCH2 gene and BOC gene promoters [Homo sapiens]
[Pathway:5635851] GLI proteins bind promoters of Hh responsive genes to promote transcription [Homo sapiens]
[BlackBoxEvent:5635853] Hh-dependent expression of GLI1 gene [Homo sapiens]
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