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Query author contributions in Reactome

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Details on Person Patched1 regulates hedgehog signaling at the primary cilium

Class:IdLiteratureReference:5610261
_displayNamePatched1 regulates hedgehog signaling at the primary cilium
_timestamp2014-07-22 19:30:05
author[Person:5609871] Rohatgi, Rajat
[Person:5358108] Milenkovic, Ljiljana
[Person:5358151] Scott, Matthew P
created[InstanceEdit:5610260] Rothfels, Karen, 2014-07-22
journalScience
pages372-6
pubMedIdentifier17641202
titlePatched1 regulates hedgehog signaling at the primary cilium
volume317
year2007
(literatureReference)[BlackBoxEvent:5610763] PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal [Homo sapiens]
[Reaction:5632646] SMURF1/2 bind PTCH1 [Homo sapiens]
[Reaction:5632648] SMURF1/2 ubiquitinates PTCH1 [Homo sapiens]
[BlackBoxEvent:5632668] SMO translocates to the cilium [Homo sapiens]
[BlackBoxEvent:5632677] PTCH is internalized [Homo sapiens]
[Pathway:5632681] Ligand-receptor interactions [Homo sapiens]
[BlackBoxEvent:5635102] GPR161 is internalized [Homo sapiens]
[Pathway:5635838] Activation of SMO [Homo sapiens]
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No pathways have been reviewed or authored by Patched1 regulates hedgehog signaling at the primary cilium (5610261)