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Details on Person Larue, Lionel
| Class:Id | Person:5610151 |
| _displayName | Larue, Lionel |
| _timestamp | 2014-07-22 19:27:34 |
| created | [InstanceEdit:5610146] Rothfels, Karen, 2014-07-22 |
| firstname | Lionel |
| initial | L |
| surname | Larue |
| (author) | [LiteratureReference:5610152] Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4 [LiteratureReference:5637496] Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair [LiteratureReference:9825545] The tumour suppressor, miR-137, inhibits malignant melanoma migration by targetting the TBX3 transcription factor [LiteratureReference:9825809] Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression [LiteratureReference:9856941] Lineage-specific transcriptional regulation of DICER by MITF in melanocytes [LiteratureReference:9857178] Mitf regulation of Dia1 controls melanoma proliferation and invasiveness [LiteratureReference:9857242] MITF has a central role in regulating starvation-induced autophagy in melanoma [LiteratureReference:9857261] Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1 [LiteratureReference:9858083] BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma [LiteratureReference:9858091] Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin |
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No pathways have been reviewed or authored by Larue, Lionel (5610151)