Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Class:IdLiteratureReference:5609873
_displayNameThe output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
_timestamp2014-07-16 20:09:54
author[Person:5609875] Humke, Eric W
[Person:5609872] Dorn, Karolin V
[Person:5358108] Milenkovic, Ljiljana
[Person:5358151] Scott, Matthew P
[Person:5609871] Rohatgi, Rajat
created[InstanceEdit:5609874] Rothfels, Karen, 2014-07-16
journalGenes Dev.
pages670-82
pubMedIdentifier20360384
titleThe output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
volume24
year2010
(literatureReference)[Reaction:5610723] GLI proteins bind SUFU [Homo sapiens]
[BlackBoxEvent:5635102] GPR161 is internalized [Homo sapiens]
[BlackBoxEvent:5635841] GLI proteins are phosphorylated [Homo sapiens]
[BlackBoxEvent:5635843] GLI translocates to the nucleus [Homo sapiens]
[BlackBoxEvent:5635854] GLI2,3 are degraded by the proteasome [Homo sapiens]
[Reaction:5635855] phosphorylated GLI proteins bind SPOP:CUL3:RBX1 [Homo sapiens]
[Reaction:5635856] SPOP:CUL3:RBX1 ubiquitinates GLI2,3 [Homo sapiens]
[Reaction:5635859] GLI:SUFU dissociates [Homo sapiens]
[BlackBoxEvent:5635860] GLI:SUFU translocates to the ciliary tip in response to Hh signaling [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins (5609873)